Eye: omeprazole in excess increases the probability of serious kidney disease


Omeprazole is one of the most popular heartburn medications, but little is known about its dangers.

In recent years it has been proven that its excessive use can bring serious consequences to our body, and can even make us more prone to stomach cancer.

A recent study conducted by the University of California at San Diego revealed that excessive use of proton pump inhibitor (PPI) drugs (such as omeprazole) increases the chances of kidney damage:

-a chronic kidney disease (28.4 times more)
-an acute kidney injury (4.2 times more)
-end-stage renal disease (35.5 times more)
-unspecified renal impairment (8 times more)

The data revealed that these conditions are aggravated by 5.6% for patients taking PPI drugs compared to those taking only histamine-2 receptor blockers.

Dr. María Jiménez Martínez, from the UNAM Faculty of Medicine, who coordinates the postgraduate course in Clinical Pharmacology and one of her lines of research is drug safety, indicated that all drugs can have adverse reactions, so the data from said study are correct and he recalled that for two years different analyzes have been carried out to understand the damage that PPIs cause to the kidneys.

A previous study speaks precisely of the association between the use of omeprazole and chronic kidney disease. And it was worrying to note that the progress of this disease rises to 70% when there is chronic use of omeprazole, because it damages the tubular cells.

The academic explained that negative factors appear when omeprazole is used in inappropriate or excessive doses or under conditions of chronic administration.

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He said that it is important that the doctor who prescribes it take into account what he intends to achieve in the patient, that is, that he knows how long the treatment will last (days, months, years) and that the patient also understands it so that he adheres to the treatment the time you need it.

But I clarify, this [las reacciones adversas] it happens with all medicines. There are no medications that you do not have and you should not be afraid to take it always following the doctor’s instructions.

The drug was developed in 1980 and its commercialization, a few years later, was positive for those who had diseases related to gastric acid.

It was an alternative to cimetidine and ranitidine, the drugs most used then to combat these problems. Omeprazole became the most important asset of that decade, and is currently one of the most important and prescribed drugs worldwide, says the UNAM Global report.

On the other hand, the academic Jiménez Martínez pointed out that omeprazole is one of the most prescribed drugs in the world, but also the most self-medicated, which is a big mistake for patients, since the effects it could bring are often unknown. taking this medication in excess.

“It is a medicine that is very useful, but it does not work miracles. It’s not that you take one and after five seconds you’re fine. We must understand that. Omeprazole does work, but it should only be used by medical indication and that the patient also make changes in the food field for it to be effective.

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-You can adequately control the secretion product of hydrochloric acid.
-Helps counteract gastroesophageal reflux.

Diarrheagas, nausea, abdominal pain, headache and constipation.
gastric lesions premalignant, such as polyps, atrophy and intestinal metaplasia (transformation of the gastric mucosa into another intestinal type).
-Increases the chances of having stomach cancer.
-Inhibition of iron absorption.
-Vitamin B12 deficiency.


Reference-aristeguinoticias.com

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